Triple Agonist
Retatrutide
Independently lab-verified GIP/GLP-1/glucagon triple agonist, HPLC & LC-MS tested.
Strength
₱4,200.00 PHP
100 units in stock · SKU RETA-10
Independently lab-verified. HPLC & LC-MS tested. Ships nationwide across the Philippines.
Product information
Research summary
Retatrutide is a 39-amino-acid synthetic peptide that engages three receptors from one sequence: the GIP receptor, the GLP-1 receptor and the glucagon receptor. It sits a generation on from dual incretin agonists, and the added glucagon-receptor arm is the reason it draws research attention — glucagon signalling contributes to hepatic substrate handling and energy expenditure in a way that incretin signalling alone does not. Published work characterises its relative potency across the three receptor populations and the consequences of shifting that balance. Preclinical and in-vitro models are used to study hepatic lipid handling, thermogenic signalling and the interaction between glucagon-driven and incretin-driven pathways. Because triple agonism is comparatively new, much of the literature is still establishing baseline pharmacology rather than downstream effect. As a newer compound it is also one where analytical verification matters most: each lot is assayed by RP-HPLC and confirmed by LC-MS, with the raw data published against the batch number.
Handling & reconstitution
Supplied lyophilised. Equilibrate the sealed vial to room temperature before opening. Reconstitute with bacteriostatic water added down the vial wall. Retatrutide carries a fatty-acid modification and behaves like its acylated relatives at the air-liquid interface — it foams when agitated. Swirl slowly and allow two to three minutes for complete dissolution; do not vortex. The finished solution should be clear and colourless. Any haze or visible particulate means the vial should not be used.
Storage
Lyophilised: -20 °C in the original sealed vial, protected from light and humidity. Reconstituted: 2–8 °C, used within approximately four weeks. Do not freeze the reconstituted solution. Retatrutide is somewhat less forgiving of temperature excursion in solution than the dual agonists, so keep it refrigerated and minimise time at room temperature during handling.
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